Tadalafil is a popular medicine taken by men to treat sexual dysfunction problems, including erectile dysfunction. It belongs to a class of drugs called PDE-5 inhibitors.
Its Mechanism of Action
Cialis 20 mg works by improving the blood flow to the penis, thus, helping men get and maintain a strong and lasting erection. However, it’s effective only when combined with sexual stimulation. This drug is also taken to treat the symptoms of BPH, or enlarged prostate. Tadalafil works by relaxing smooth muscles in the bladder and prostate.
Any penile erection is caused by filing a penis with blood, and it happens because the blood vessels that bring blood to this organ increase in size, while the ones that take the blood away reduce in size. Besides, sexual stimulation that results in erections causes the release and production of nitric oxide, which causes the production of cGMP responsible for both decreasing and increasing the size of penile blood vessels. When this important enzyme is destroyed by PDH-5, erections end because blood vessels return to their normal size. The intake of Tadalafil prevents it from destroying cGMP, thus, resulting in prolonged and stronger penile erections.
How to Use Tadalafil
Before you get generic Tadalafil online, make sure that you know how to take it correctly. Take this PDH-5 inhibitor orally, both with and without food. It’s not allowed to use this drug more often than once a day. To treat erectile dysfunction, there are two intake methods used by men. Most patients start with a low dose that can be increased or decreased based on individual tolerance to avoid possible adverse reactions.
Men who take Tadalafil as needed use their dose about 30 minutes before their planned sexual activity. The good news is that its positive effect lasts for about 36 hours, and that’s why it’s called a weekend pill. This potent ED medicine is absorbed by the stomach and released through the liver.
Mild and Severe Side Effects
There are certain Cialis side effects that you should be aware of before starting this popular ED treatment. Some of the most common mild side effects include:
- Upset stomach and stuffy nose;
- Headaches and dizziness;
- Muscle and back pain;
- Facial flushing and lightheadedness.
If any of the above-mentioned symptoms worsen or persist, call your doctor immediately. To avoid possible risk of lightheadedness and dizziness, get up slowly from any lying or sitting position. The good news is that most men who take Tadalafil don’t experience any severe side effects.
Any sexual activity may put more strain on your heart, especially if you have any pre-existing conditions. If you have any heart problems and experience the following severe side effects, stop taking Tadalafil and get emergency medical help:
- Fainting and sever dizziness;
- Nausea and chest or jaw pain.
In very rare cases, men experience sudden decreased vision, and this risk is increased if you have diabetes, heart diseases, specific eye issues, high cholesterol blood levels, hypertension, or if you smoke or are older than 50. Go to the hospital if you experience ringing in the ears or other hearing changes, prolonged or painful erections.
Serious allergic reactions to Tadalafil are very rare. You need to get medical help right after noticing such symptoms as swelling, itching, skin rash, difficulty breathing and severe dizziness.
Before starting this ED treatment, inform doctors if you have any possible allergic reactions. Report other health conditions that you have, especially liver and kidney problems, heart diseases, severe dehydration, low or high blood pressure, priapism, penis conditions, eye ailments, bleeding disorders, stomach ulcers and others.
There are other Tadalafil contraindications that you should know, so consult your physician about its safe intake. It may make you feel dizzy, so you should be careful when driving or doing other things that require full alertness. Besides, Tadalafil and alcohol are contraindicated, so you shouldn’t drink when taking this drug, because alcohol affects its absorption and mechanism of action.
There are certain pharmaceutical products that must be avoided when taking Tadalafil because of possible drug interactions. Don’t take it along with nitrates, riociguat, recreational drugs, alpha-blockers, azole antifungals, HIV protease inhibitors, macrolide antibiotics, rifampin and hepatitis C virus protease inhibitors.